The biggest drawback to this solution is that your full layout must fit on your screen.
You can then copy and paste that image wherever you need it. Once your rectangle is complete and you release the mouse button, it will automatically paste an image of your selection into an unfiled OneNote page. This will give you a cross hairs mouse and allow you to draw a rectangle around any part of your visible screen. When your layout is complete, hold down the WINDOWS button and press S.
In this scenario, you need to create your desired layout in another software program such as Microsoft Word or Publisher. If you need a more sophisticated layout, such as an image surrounded by closely wrapped text on all sides, then this solution might be your better option. Text wrapped image in OneNote using the WINDOWS + S technique.